R methylammonium uptake in cells (267). In a molecular dynamics study of (methyl) ammonium transport, it was concluded that conduction through the pore is facilitated by the hydrogen bond network comprised of both histidines and Tyr32 in coordination with interactions with Trp212. In particular, Trp212 would be important for removing NH3 from its strong hydrogen bonding to His168 (291). Deprotonat