Tudied member of the Lrp family (241) or the FFRP (feast/famine regulatory protein) family (242). Because many reviews (6, 241?244) dealing with Lrp can be found in the literature, we only summarize here. Lrp is a small protein ( 19 kDa) (244). It consists of an N-terminal DNA binding domain, harboring the canonical helix-turnhelix motif, connected with a flexible hinge to a C-terminal ligand bind