Ing inhibitor yd47 prevents biofilm formation in vitro and OM in a guinea pig model.87 Macrolides and fluoroquinolones are the most effective antibiotics for disrupting biofilms in vitro.88 The sensitizing milk protein HAMLET increases the potency of antibiotics to both sensitive and resistant pneumococcal strains.89 Complement: Phosphoglycerate kinase and elongation factor Tu were shown to be pne