Individual subunit c isoforms prompted us to investigate the assembly of the oxidative phosphorylation system complexes by BN-PAGE and Western blot. Individual silencing of each of the three subunit c isoforms translated into a similar modest destabilization of ATPase (Figure 5A). Densitometric analyses revealed a reduction in the content of fully assembled ATPase (P1, 17.3 2.5 , p 0.05; P2, 23.5