Iant. Arthritis Rheum. 2005; 52(1):212?18. [PubMed: 15641049] 21. Hirose N, Williams R, Alberts A, et al. A role for the polymorphism at position 247 of the 2glycoprotein I gene in the generation of anti-2-glycoprotein I antibodies in the antiphospholipid syndrome. Arthritis Rheum. 1999; 42(8):1655?661. [PubMed: 10446865] 22. Pernambuco-Climaco J, Brochado M, Frietas M, Roselino A, Louzado-Junior