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Ns, plasma levels of CRP are below 3 mg/L under normal conditions but could increase up to 1000 folds in 48 hours during the acute-phase response; this is not true for SAP plasma levels which are relatively stable (30?0 mg/L) even during the acute-phase response [6]. PTX3, which is the prototypic long pentraxin, was identified in the early 1990s, as a molecule rapidly induced by IL-1 in endothelia
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