Tide remains compact(202) or displays a rather independent Nterminus.(195) In particular, the latter simulation showed that the D23N mutation causes nonlocal perturbations of the WT conformational ensemble by increasing the -sheet propensity at the C-terminal region. This result is in agreement with the ss-NMR structure of a highly synaptic A1-40 toxic oligomer with a stable N-terminal -strand.(12

Ing inhibitor yd47 prevents biofilm formation in vitro and OM in a guinea pig model.87 Macrolides and fluoroquinolones are the most effective antibiotics for disrupting biofilms in vitro.88 The sensitizing milk protein HAMLET increases the potency of antibiotics to both sensitive and resistant pneumococcal strains.89 Complement: Phosphoglycerate kinase and elongation factor Tu were shown to be pne

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