As hepatosplenomegaly. The maximum diameter of the paraaortic lymph nodes was 8 cm (Fig. 2A). We diagnosed a relapse of CLL based on the increased lymphocyte count and sIL-2R level in peripheral blood. As the patient's disease was refractory to the previous chemotherapies, bendamustine was administered at a dose of 70 mg/m2/day for 2 days and this was repeated on days 42?3, 98?9, and 182?83 [19] w