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Positioning these proteins at the site of the developing exosporium (57, 58, 65?7). No such localization domain is present in the BxpB sequence. Therefore, my colleagues and I have proposed a model whereby BxpB is delivered to the spore by virtue of forming a complex with BclA and possibly, to a lesser extent, with other exosporium-targeting motif sequences (58). In keeping with this, we observed

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Protection has, in fact, been achieved by administering polyclonal and monoclonal antiHIV-1 neutralizing antibodies (NAbs) to humanized mice or macaques prior to challenge with SIV/HIV chimeric viruses (SHIVs)1-8. During the past seven years, monoclonal antibodies (MAbs) have been isolated from selected HIV-1 infected individuals, who generate anti-viral NAbs (bNAbs) with broad and potent activity

H HIV/ AIDS from South Africa poignantly highlighted issues of violence and abuse, among others, in her relationship with her partner, following disclosure of her positive HIV status [34]. Another study carried out in Chennai, India, among female sex workers showed that they feared the adverse consequences of disclosure of their positive HIV statuses due to the stigma and discrimination associated

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