Pelleted in a conical tube and washed with cold phosphate-buffered saline. Sonication and immunoprecipitation were performed using Chromatin Immunoprecipitation (ChIP) Assay Kit (Upstate) according to the manufacturer's instructions. Antibodies used are presented in Table S2. As negative control, normal rabbit or mouse serum (Sigma-Aldrich) was used. Appropriate primer pairs (Table S1) were used t
O two comparable criteria: an epidemiologic efficiency criterion and an equity criterion.Efficiency criterionWe look at the effect over a year of the MC intervention on the male population, by calculating the risk of a man Rm getting infected by his female partner. This allows us to use a static model of transmission. The model does not look at the effect on the female population as there is not y
O two comparable criteria: an epidemiologic efficiency criterion and an equity criterion.Efficiency criterionWe look at the effect over a year of the MC intervention on the male population, by calculating the risk of a man Rm getting infected by his female partner. This allows us to use a static model of transmission. The model does not look at the effect on the female population as there is not y
R (1.825 and 6.446 g/ml) and were also in the same range as the IC80 values determined in vitro. It is worth noting that three of the six recipients of the 10-1074 MAb experienced rapid decay of plasma antibody, which fell to background levels between weeks 4 to 6 following administration (Fig. 3c). A similar pattern occurred for three of the 3BNC117 MAb and VRC01-LS recipients, although the decli
R (1.825 and 6.446 g/ml) and were also in the same range as the IC80 values determined in vitro. It is worth noting that three of the six recipients of the 10-1074 MAb experienced rapid decay of plasma antibody, which fell to background levels between weeks 4 to 6 following administration (Fig. 3c). A similar pattern occurred for three of the 3BNC117 MAb and VRC01-LS recipients, although the decli