Ination findings. Given the inhibition of HSV-2 replication observed after administration of tenofovir, it is biologically plausible that FTC/ TDF reduced the frequency or severity of ulcers. Unlike acyclovir, tenofovir does not require the presence of the herpes virus for drug activation, suggesting that it may suppress ulcers before phosphorylation occurs. However, topical dosing may be required
H HIV/ AIDS from South Africa poignantly highlighted issues of violence and abuse, among others, in her relationship with her partner, following disclosure of her positive HIV status [34]. Another study carried out in Chennai, India, among female sex workers showed that they feared the adverse consequences of disclosure of their positive HIV statuses due to the stigma and discrimination associated
Egrative theories of gender [10]. This theory is important because it allows for an understanding of the complex interplay between gender and power beyond the individual perspective. A central emphasis of this theory is that the analysis of gender involves a three-part structural model involving sexual division of labour (e.g. financial inequality), sexual division of power (e.g. authority), and t
Idence of 6.1 per 100 person-years) and 60 were in the placebo group (incidence of 5.6 per 100 person-years). There was no significant difference in time to HSV-2 incidence among participants assigned to the FTC/TDF arm compared with those assigned to the placebo arm (HR 1.1, 95 CI: 0.8?.5; P = 0.64; Figure 2). Compared with participants in the placebo arm, there was also no difference in time to
H condom, past 3 months Yes No Insertive anal intercourse with no condom, past 3 months Yes No Receptive anal intercourse with condom, past 3 months Yes No Receptive anal intercourse with no condom, past 3 months Yes No 671 (50) 676 (50) 617 (46) 730 (54) 802 (60) 545 (40) 681 (51) 666 (49)cEvents/PY 125/Incidence density 5.Unadjusted HRb (95 CI)Adjusted HR (95 CI) P-value0.02 809 (60) 271 (20)
Cial mechanisms. Connell's theory of gender and power has been shown previously to explain the gender effects in the spread of HIV/AIDS infection [11,12]. Sa and Larsen applied this theory in their study in Moshi, Tanzania, using gender inequality to explain women's risk of HIV infection [12]. In this study, we adopt Connell's theory of gender and power as a theoretical framework to explore and cl
Cial mechanisms. Connell's theory of gender and power has been shown previously to explain the gender effects in the spread of HIV/AIDS infection [11,12]. Sa and Larsen applied this theory in their study in Moshi, Tanzania, using gender inequality to explain women's risk of HIV infection [12]. In this study, we adopt Connell's theory of gender and power as a theoretical framework to explore and cl
Pared to ST, and the proportion of Treg as well as the Th17/Treg ratio was normalized following ART (data not shown). Interestingly, plasma sCD40L levels were correlated with increased Treg frequency (P = 0?1, r = 0?001) (Fig. 2b) and a low Th17/Treg ratio in all HIV-infected patients (P = 0?08, r = ??210) (Fig. 2c). Such a correlation was not observed with Th17 cell frequency (P = 0?7, data not s