O column totals due to missing data. doi:10.1371/journal.pone.0091513.tparticipants reported taking over 90 of study drug doses, drug was detectable in the blood specimens of only 50 of participants tested in a random subsample.[13] Although we did not observe an effect of FTC/TDF even after accounting for drug levels, it may be that oral FTC/TDF will be shown to have an impact on HSV-2 incidenc
Cial mechanisms. Connell's theory of gender and power has been shown previously to explain the gender effects in the spread of HIV/AIDS infection [11,12]. Sa and Larsen applied this theory in their study in Moshi, Tanzania, using gender inequality to explain women's risk of HIV infection [12]. In this study, we adopt Connell's theory of gender and power as a theoretical framework to explore and cl
Tate, Nigeria. These three different populations coincide with Connell's gender and power theory, which explores gender-related differences at different levels: family level (PLWHA), societal level (the general public) and health care institution level (HCPs). We compared results obtained from the three groups. For the general public, a convenience sample of persons (16 males and 24 females) was u
Ollow-up; if use of these medications biased our analysis toward the null, it is possible that the effect of FTC/TDF on ulcers is stronger than what we observed in our study. Our behavioral risk factor analysis included number of anal sex partners, position during anal sex, and condom use in the lastDaily Oral FTC/TDF PrEP and HSV-2 among MSMTable 2. Baseline characteristics by time to HSV-2 seroi
Erships. Two coders with extensive front-line work experience independently coded the data until saturation occurred and no new themes emerged (Charmaz, 2000), using well-established procedures for thematic analysis (Neuendorf, 2002). We used a modified form of grounded theory (Strauss Corbin, 1990), where our theoretical orientations, analytic training and skills, and experience with the data i
Erships. Two coders with extensive front-line work experience independently coded the data until saturation occurred and no new themes emerged (Charmaz, 2000), using well-established procedures for thematic analysis (Neuendorf, 2002). We used a modified form of grounded theory (Strauss Corbin, 1990), where our theoretical orientations, analytic training and skills, and experience with the data i
Nd quantitative phases sequentially; however, we show in the sections below how data analyses and interpretation occurred concurrently. Qualitative Phase For this phase, 20 providers were recruited from 10 agencies to give in-depth interviews about their involvement in HIV research. These 10 agencies were selected randomly from a list of agencies funded by the New York City Department of Health an
Er implement the study and analyze and interpret the data collected. They will--to the degree possible--jointly disseminate results via scientific journals and conferences. They will also jointly disseminate results via community-based publications and conferences. Agency size and research capacity: We used four distinct measures of agency size/ capacity. Agency budget was measured as small (less