N of cRAI in the past three months being reported more frequently in the placebo arm (P = 0.01). Of the 1,383 participants who tested seronegative for HSV-2 at baseline, 36 (2.6 ) did not contribute person-time to incidence analyses because they were retrospectively found to be HIVinfected at baseline, tested seropositive for HSV-2 at the enrollment visit subsequent to screening, or were lost to f
D ,25 years (7.1 per 100 person-years) and the lowest rate among participants aged 40 years (1.6 per 100 person-years; P trend = 0.001). Country of residence was also associated with HSV-2 incidence, with theDaily Oral FTC/TDF PrEP and HSV-2 among MSMthere were 72 ulcer AEs classified as Grade 2 or above, with 43 participants (4.3 ) having 1 ulcer AE. Among the 72 ulcer AEs, 23 (31.9 ) were conf
N of cRAI in the past three months being reported more frequently in the placebo arm (P = 0.01). Of the 1,383 participants who tested seronegative for HSV-2 at baseline, 36 (2.6 ) did not contribute person-time to incidence analyses because they were retrospectively found to be HIVinfected at baseline, tested seropositive for HSV-2 at the enrollment visit subsequent to screening, or were lost to f
Nversion to determine whether there were differences in ulcer occurrence by randomization group in the absence of study drug. All analyses were conducted in SAS 9.3 or Stata 12.Results Study participantsCharacteristics of the 2,499 iPrEx participants have been described previously. [13] Briefly, all participants were born male and 313 (13.0 ) identified as transgender or as women. The mean age at
D ,25 years (7.1 per 100 person-years) and the lowest rate among participants aged 40 years (1.6 per 100 person-years; P trend = 0.001). Country of residence was also associated with HSV-2 incidence, with theDaily Oral FTC/TDF PrEP and HSV-2 among MSMthere were 72 ulcer AEs classified as Grade 2 or above, with 43 participants (4.3 ) having 1 ulcer AE. Among the 72 ulcer AEs, 23 (31.9 ) were conf
S in Nigeria [16]. The inheritance laws that favour men place women in economically disadvantaged positions, which make women more vulnerable to infection with HIV/ AIDS and its problems. Research carried out among HIVpositive women in Abia state, Nigeria showed that 86.7 of the women in the study were denied rights to family resources [20]. It is also generally accepted that sons provide continu
S in Nigeria [16]. The inheritance laws that favour men place women in economically disadvantaged positions, which make women more vulnerable to infection with HIV/ AIDS and its problems. Research carried out among HIVpositive women in Abia state, Nigeria showed that 86.7 of the women in the study were denied rights to family resources [20]. It is also generally accepted that sons provide continu
Among females aged 15-24 years was* Correspondence: ngozicmbonu@yahoo.comDepartment of Health Promotion, School of Public Health and Primary Care CAPHRI Faculty of Health, Medicine and Life Sciences, Maastricht University, PO Box 616, Maastricht 6200 MD, The NetherlandsFull list of author information is available at the end of the article2.3 in 2008 while the prevalence rate among males aged 15-2