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Expressed by the candidate vaccines were derived from an HIV-1 isolate from a vertically HIV-1-infected infant designated as C58A1 (subtype B). The env gene contained the immunodominant portion of gp41. The tat, rev, nef and reverse transcriptase (RT) genes were modified to render the proteins non-functional. These genes were inserted into two MVA and two FPV vectors; one of each pair containing e