G directly administered antiretroviral therapy with self-administered therapy in opioid treatment programs, Baltimore, Maryland, 2006?010.Differencea (95 CI)SAT (N = 52) Virologic and immunologic outcomes Average proportion with HIV RNA ,50 copies/mL during interventionb Average proportion with HIV RNA ,400 copies/mL during intervention Average change from baseline in log10 HIV RNA during interve
Ow-up will be needed to determine whether HCV cure through the use of direct-acting antivirals among HIV/ HCV coinfected elite controllers will make the risk for complications among these patients similar to their HIV monoinfected counterparts. Further studies will also be needed to determine the effects of antiretroviral therapy in this group of patients coupled to its risk/benefit ratio. Whereas
Phase and baseline in the SAT arm, while the coefficient X3 represented thedifference between DAART and SAT in the odds of viral suppression during the intervention phase versus baseline. The model accounted for the intra-person dependency of observations using the generalized estimating equation (GEE) approach [13] for parameter estimation and assuming a uniform correlation between any pair of re
Phase and baseline in the SAT arm, while the coefficient X3 represented thedifference between DAART and SAT in the odds of viral suppression during the intervention phase versus baseline. The model accounted for the intra-person dependency of observations using the generalized estimating equation (GEE) approach [13] for parameter estimation and assuming a uniform correlation between any pair of re
Nt populations [6,7]. Opioid treatment programs (OTPs) provide a potential framework for DAART because patients visit multiple times each week to receive opioid agonist medication. Moreover, maintenance treatment at OTPs permits prolonged DAART, which is difficult in models based on outreach workers. Based on promisingDirectly Administered Therapy for HIVFigure 1. Study screening, enrollment, and