Onents of MetS in ER/PR-negative patients (P for trend = 0.044). This association disappeared when adjusted for adiponectin and HOMA-IR. Conclusions: Adiponectin and HOMA-IR have prognostic significance in breast cancer recurrence and interventions related to these factors may protect against recurrence in ER/PR-negative patients. These findings were not observed in the case of ER/PR-positive pati
Ly, 681 cases (91.2 ) were ductal carcinomas and 66 cases (8.8 ) were of other types (lobular, medullary, mucinous, papillary, or tubular carcinoma). Mean age at inclusion time was 45.9 ?9.8 (mean ?SD) years and 31.3 were postmenopausal women (Table 1). Most baseline characteristics did not differ between the ER/PR-negative and -positive groups (all Ps > 0.05; Table 1, some data not shown). Howev
Ly, 681 cases (91.2 ) were ductal carcinomas and 66 cases (8.8 ) were of other types (lobular, medullary, mucinous, papillary, or tubular carcinoma). Mean age at inclusion time was 45.9 ?9.8 (mean ?SD) years and 31.3 were postmenopausal women (Table 1). Most baseline characteristics did not differ between the ER/PR-negative and -positive groups (all Ps > 0.05; Table 1, some data not shown). Howev
Ed two models. Model 1 was constructed using variables with P
Nalyses, and provided critical revision of the manuscript. PNS provided critical revision of the manuscript and participated in the study design. VdW and AvG performed the laboratory work and provided critical revision of the manuscript. JAF and JWMM participated in the study design, provided the study material and clinical information, and provided critical revision of the manuscript. GJA partici
Nalyses, and provided critical revision of the manuscript. PNS provided critical revision of the manuscript and participated in the study design. VdW and AvG performed the laboratory work and provided critical revision of the manuscript. JAF and JWMM participated in the study design, provided the study material and clinical information, and provided critical revision of the manuscript. GJA partici
Ariable in subgroups of tumors stratified by steroid hormone receptor status and tumor size (Table 3 and Figure 1). Subdividing the 837 primary LNN tumors into ESR1-positive and -negative [14] showed that increasing levels of DCSCRIPT were, in univariate and multivariable analyses, associated with good prognosis only for the patients with ESR1-positive tumors. Subdividing these LNN tumors at the m
Early breast cancer. The patients described in thisSieuwerts et al. Breast Cancer Research 2010, 12:R103 http://breast-cancer-research.com/content/12/6/RPage 7 ofTable 3 Disease-free survival, metastasis-free survival, and overall survival as a function of continuous DC-SCRIPT in lymph node-negative diseaseAssociation with continuous DC-SCRIPT Cohort Lymph node-negative ESR1 mRNA-negativea ESR1 mR