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Rial. JAMA 2009, 301(15):1547?555. American Diabetes Association: Diagnosis and classification of diabetes mellitus. Diabetes Care 2004, 27(Suppl 1):s5 10. Grundy S, Brewer HBJ, Cleeman J, Smith SC, Lenfant C: Definition of metabolic syndrome report of the National heart, lung, and blood Institute/American heart association conference on scientific issues related to definition. Circulation 2004, 1
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Rial. JAMA 2009, 301(15):1547?555. American Diabetes Association: Diagnosis and classification of diabetes mellitus. Diabetes Care 2004, 27(Suppl 1):s5 10. Grundy S, Brewer HBJ, Cleeman J, Smith SC, Lenfant C: Definition of metabolic syndrome report of the National heart, lung, and blood Institute/American heart association conference on scientific issues related to definition. Circulation 2004, 1
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Task force for the redefinition of myocardial infarction. Universal Definition of Myocardial Infarction. Eur Heart J 2007, 28:2525?538. Budoff MJ, Nasir K, McClelland RL, Detrano R, Wong N, Blumenthal RS, Kondos G, Kronmal RA: Coronary calcium predicts events better with absolute calcium scores than age-sex-race/ethnicity percentiles: MESA (Multi-Ethnic Study of Atheroslcerosis). J Am Coll Cardiol
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Non-calcified plaques, of which one (1.2 ) was obstructive (Table 2). Coronary atherosclerosis was completely absent in 32.9 of patients.Follow-up: impact of CT results on treatment and cardiovascular risk profileSubsequent to CT results, 7.1 of patients underwent percutaneous revascularisation. Medical therapy was optimised in 25.9 patients: 4.7 started ACE inhibitors/ ARB , 12.9 were put on
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To evaluate a potential association with the study endpoints. Cox regression (method Forward Conditional) was performed to identify the independent predictors of cardiovascular events over time. Treatment started after CT (revascularisation, antiplatelet agents, statins) and duration of diabetes were also regarded. The discriminatory power of cardiovascular events predictors was then evaluated thr
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Utoff point the Youden index, which is the point on the ROC curve where optimal sensitivity and specificity are achieved. Predictor models were created trough multivariate analysis (binary logistic regression with the method Enter) using events predictors (as continuous variables whenever possible): Clinical model, comprising GFR, age and Framingham evaluated before CT; CT model, comprising CS, ob
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Utoff point the Youden index, which is the point on the ROC curve where optimal sensitivity and specificity are achieved. Predictor models were created trough multivariate analysis (binary logistic regression with the method Enter) using events predictors (as continuous variables whenever possible): Clinical model, comprising GFR, age and Framingham evaluated before CT; CT model, comprising CS, ob
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Fraction by the heart failure and echocardiography associations of the European society of cardiology. Eur Heart J 2007, 28:2539?550. Devereux RB, Reichek N: Echocardiographic determination of left ventricular mass in man: anatomic validation of the method. Circulation 1977, 55:613?18.25. Pollentier B, Irons SL, Benedetto CM, Dibenedetto AM, Loton D, Seyler RD, et al: Examination of the six minute