F a CCR5-antagonist-based treatment4,5. Deep sequencing techniques can detect minor variants, especially ones that use CXCR46?. The 454 GS-Junior sequencing platform (Roche) can reliably predict HIV-1 tropism9?1. The Ion Torrent Personal Genome Machine has also been validated for tropism determination12. Another study evaluated the Illumina platform for determining HIV-1 drug resistance and HIV-1
Use, F-31300, France. 3CHU de Toulouse, H ital Purpan, Laboratoire de Virologie, Toulouse, F-31300, France. 4CHU de Toulouse, H ital Purpan, Service des Maladies Infectieuses et Tropicales, Toulouse, F-31300, France. Correspondence and requests for materials should be addressed to S.R. (email: raymond.s@chu-toulouse.fr)Scientific RepoRts | 7:42215 | DOI: 10.1038/srepResultswww.nature.com/scientifi
Use, F-31300, France. 3CHU de Toulouse, H ital Purpan, Laboratoire de Virologie, Toulouse, F-31300, France. 4CHU de Toulouse, H ital Purpan, Service des Maladies Infectieuses et Tropicales, Toulouse, F-31300, France. Correspondence and requests for materials should be addressed to S.R. (email: raymond.s@chu-toulouse.fr)Scientific RepoRts | 7:42215 | DOI: 10.1038/srepResultswww.nature.com/scientifi
Nding gendered influences on women's reproductive health in Pakistan: moving beyond the autonomy paradigm. Soc. Sci. Med., 68(7), 1349-56. http://dx.doi.org/10.1016/j.socscimed.2009.01.025 National Institute of Population Studies (NIPS) Islamabad Pakistan Macro International Inc. USA (June 2008). Pakistan Demographic and Health Survey 2006-07. Patton, M. Q. (1999). Enhancing the quality and credib
D Z13e1) bind to epitopes at the base of gp41, along a segment adjacent to the viral membrane known as the membrane proximal external region (MPER) that links the gp41 transmembrane domain to its ectodomain [2,3]. Two, 4E10 and 2F5, have been extensively characterized. Each has been shown to be polyreactive [4?], with an elongated heavy chain complementarity determining region 3 (CDRH3) that has a
Nts in clinical practice but technical optimization are needed to improve quantification. Human immunodeficiency virus (HIV) enters its host cells following the interaction between the virus envelope glycoprotein (Gp120), the cell surface CD4 receptor, and a chemokine receptor, which may be CCR5 and/ or CXCR4, acting as a coreceptor1. The HIV tropism is defined by the coreceptor(s) use and is corr
Nts in clinical practice but technical optimization are needed to improve quantification. Human immunodeficiency virus (HIV) enters its host cells following the interaction between the virus envelope glycoprotein (Gp120), the cell surface CD4 receptor, and a chemokine receptor, which may be CCR5 and/ or CXCR4, acting as a coreceptor1. The HIV tropism is defined by the coreceptor(s) use and is corr
Ic? Findings from a population based study in Karachi, Pakistan. BMC Infect. Dis., 9, 38. http://dx.doi.org/10.1186/1471-2334-9-38 Fox, M. P., Mazimba, A., Seidenberg, P., Crooks, D., Sikateyo, B., Rosen, S. (2010). Barriers to initiation of antiretroviral treatment in rural and urban areas of Zambia: a cross-sectional study of cost, stigma, and perceptions about ART. J. Int. AIDS Soc., 13, 8. h