W the limit of detection ( LOD), below the lowest calibration standard ( LLOQ), or quantified based on a ratio to a class-based internal standard (semiquantitative). Each analyte was normalized for the total protein in the sample, concentrations shown in supplemental Table S5. Oxylipin Assay of Middle Ear Mucosae-- Preparation of Oxylipin Standards--Stable isotope labeled (SIL) oxylipin standard s
Are part of a large chaperone multiprotein complex and inhibit aggregation of misfolded proteins that play a role in the folding of disulfide-bonded proteins; P4hb, prolyl 4-hydroxylase beta polypeptide, also a member of the protein disulfide isomerase family and at low concentrations facilitates protein aggregation (anti-chaperone) whereas at high concentrations inhibits protein aggregation (chap
Ns of the microtubule. There is another level of complication with regard to the issue of microtubule cold-stability. As defined above, the cold-stable fraction is that fraction of the microtubule mass that is resistant to depolymerization by cold in biochemical preparations. However, the same rules about microtubule cold stability do not apply to cells that are intact. When intact cells are expos
Ia neuroligins. Cell. 2004; 119:1013?6. [PubMed: 15620359] Grunwald IC, Korte M, Wolfer D, Wilkinson GA, Unsicker K, et al. Kinase-independent requirement of EphB2 receptors in hippocampal synaptic plasticity. Neuron. 2001; 32:1027?0. [PubMed: 11754835] Haase G, Dessaud E, Garces A, de Bovis B, Birling M, et al. GDNF acts through PEA3 to regulate cell body positioning and muscle innervation of spe
Lar Cellular Proteomics 14: 10.1074/mcp.O115.049957, 3094?104, 2015. The dried blood spot (DBS)1 methodology provides several advantages over traditional plasma or serum samples throughout the entire pre-analytical workflow including sample collection, transportation, and storage (1, 2) These blood samples are typically generated using a small sterile lancet to prick the skin and then spotting a
H these results might suggest a specific nature of Nup124p's FXFG-domain requirement, it is possible that Nup124p interacts in a similar manner with proteins, such as transport factors, other nucleoporins, none of which are essential for viability and therefore unaffected by overexpression of the FXFG domain. The growth rate is not affected upon overexpressing these domains, indicating that essent
Fact that these effectors of the innate immune system are highly up-regulated at the transcription level after immune challenge. Other highly induced proteins include heat shock protein (HSP) 25.4's, lipases, esterases, peptidases, lipidbinding proteins, and some hypothetical proteins. While some of them mediate metabolic changes in response to the stressMolecular Cellular Proteomics 15.Proteomi
Fact that these effectors of the innate immune system are highly up-regulated at the transcription level after immune challenge. Other highly induced proteins include heat shock protein (HSP) 25.4's, lipases, esterases, peptidases, lipidbinding proteins, and some hypothetical proteins. While some of them mediate metabolic changes in response to the stressMolecular Cellular Proteomics 15.Proteomi