64188 - High DR Web Submission Directory - Xpressed proteins. Functional Validation of Interactions by shRNA-Mediated Knockdown--To determine the http://64188.org/story.php?title=xpressed-proteins-functional-validation-of-interactions-by-shrna-mediated-knockdown-to-determine-the-8 Xpressed proteins. Functional Validation of Interactions by shRNA-Mediated Knockdown--To determine the extent to which the high confidence interactors identified by I-DIRT play a role in DENV infection, we used shRNA to silence a panel of host genes and then determined the effect on DENV infection. The genes in our panel included interactors of both NS5-GFP and NS3GFP (CAD, DHCR7), only NS5-GFP (M Tue, 16 May 2023 17:54:42 UTC en