64188 - High DR Web Submission Directory - To cause less complement-mediated pain and fewer hypersensitivity reactions than ch http://64188.org/story.php?title=to-cause-less-complement-mediated-pain-and-fewer-hypersensitivity-reactions-than-ch To cause less complement-mediated pain and fewer hypersensitivity reactions than ch14.18. We conducted a phase I trial of hu14.18K322A in children with refractory or recurrent neuroblastoma to define the toxicity profile, dose-limiting toxicities (DLTs), maximum-tolerated dose (MTD), pharmacokinetics, and immunogenicity of this novel antiGD2 antibody.PATIENTS AND METHODSPatient Population Eligibil Fri, 19 May 2023 02:19:27 UTC en