http://64188.org/story.php?title=s-a-link-between-cd40-and-microglia-has-been-established-upregulation-5 S, a link between CD40 and microglia has been established. Upregulation of CD40 expression has been detected on microglia of HIV-1-infected brain tissues [28]. CD40L was also shown to potentiate the ability of HIV-1 Tat to activate monocytes and microglia leading to the overproduction of inflammatory proteins such as cytokines and chemokines [122]. Furthermore HAART is unable to modulate blood bra Thu, 11 May 2023 15:09:39 UTC en