64188 - High DR Web Submission Directory - Port, we show that soluble mimics of CD4 inhibit HIV-1 infection http://64188.org/story.php?title=port-we-show-that-soluble-mimics-of-cd4-inhibit-hiv-1-infection-2 Port, we show that soluble mimics of CD4 inhibit HIV-1 infection by prematurely triggering the viral envelope glycoproteins. The unstable activated state of the virus lasts only a few minutes, after which the virus loses the ability to infect cells. This novel strategy for inhibition may be generally applicable to other viruses besides HIV-1, some of which are also activated by binding to their re Wed, 17 May 2023 14:00:50 UTC en