http://64188.org/story.php?title=mic-blasts-at-diagnosis-the-values-of-the-aai-profile-increased-9 Mic blasts at diagnosis. The values of the AAI profile increased again at relapse, indicating apoptosis-resistance (11). Based on these unexpected findings, we hypothesized that expression of apoptosis-related proteins in AML blasts, and possibly also in bystander cells in the bone marrow, is regulated by extracellular factors present in the AML microenvironment. Tumor cell communication with its Tue, 17 Jan 2023 05:16:32 UTC en