http://64188.org/story.php?title=help-shed-light-on-structural-determinants-of-gpcr-activity-more-specifically Help shed light on structural determinants of GPCR activity. More specifically, the use of G proteins to capture pathway-specific conformations could reveal binding opportunities associated with ligand trafficking in either the receptor's orthosteric domain or elsewhere on more accessible and less conserved regions of the GPCR. Furthermore, structures of protein complexes such as GPCR-G protein, G Thu, 19 Jan 2023 02:45:51 UTC en