http://64188.org/story.php?title=d-analgesic-efficacy-therefore-tlrs-may-play-a-pivotal-sensing-role-1 D analgesic efficacy. Therefore, TLRs may play a pivotal sensing role for the innate immune system within the CNS by detecting the presence of drugs, such as opioids, and translating their presence into a central immune signal. Among the other pattern-recognition receptors, of which there are several types, the nucleotide-binding domain leucine-rich repeat-containing receptors (NLRs) are also key Tue, 09 May 2023 03:16:07 UTC en