http://64188.org/story.php?title=amic-changes-in-conformation-and-function-of-the-hiv-1-envelope-glycoproteins-2 Amic changes in conformation and function of the HIV-1 envelope glycoproteins, immediately after engagement of the activating molecules. Using these tools, we found that SCMs inactivate envelope glycoprotein function by an activation-triggered inhibition process, through induction of a metastable activated state.Materials and Methods Reagents and AntibodiesFour-domain sCD4 (molecular weight 50 kDa Wed, 10 May 2023 05:10:07 UTC en