Imated OTP retention at 6 and 12 months were 78 and 60 in DAART, and 83 and 73 in SAT, respectively (HR for OTP discontinuation in DAART versus SAT, 1.3; 95 CI, 0.7?.4). During the intervention phase, the average proportions with urine drug tests positive for opiates or cocaine were 0.33 and 0.37 in DAART and SAT, respectively (difference 20.04, 95 CI 20.18 to 0.10).Primary Viral Load Outcom

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Milar to that of AD. b-amyloid is a potent and direct neurotoxic agent [77-79], much like the HIV-1 proteins gp120 and Tat, and it induces a cascade of cellular mechanisms including activation of microglia [80], which leads to neuronal damage [81]. Indeed, reactive microglia are closely associated with neuritic and b-amyloid plaques, just as they are with HIV1 Tat protein [82-89]. Using electron m

Either ESR1-positive and/or ESR2-low pT1 tumors.Introduction Estrogens influence the aggressiveness of breast cancer through their cognate nuclear receptors. In particular, the estrogen receptor-alpha (ERa) (ESR1) - present in tumor cells of about 70 to 75 of all breast tumors is considered crucial because of its proliferationinducing actions and for that reason is an important target for therap

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Ve CRE sites were able to bind recombinant CRE binding-bZIP proteins, conditions under which these CRE sites come into play in native neurons are unknown. GluA1 receptors (like all AMPA receptor subunits) are expressed by neurons and glial cells in vivo and in vitro (Gallo and Ghiani, 2000), but the density of functional receptors is much lower in astrocytes than neurons. In oligodendrocyte progen