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E to the periplasmic cytochrome c peroxidase encoded by ccp (Archibald and Duong, 1986). ccp mutant Gc show slight sensitivity to hydrogen peroxide, which is markedly enhanced when katA is also inactivated (Turner et al., 2003). Gc also imports Mn(II) into its cytoplasm via the MntABC transporter, where it scavenges superoxide and hydrogen peroxide by a mechanism independent of SodB and catalase (

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Coproteins [1]. Binding of gp120 to the receptor, CD4, on the target cell surface induces major conformational changes in the envelope glycoproteins [2]. These changes allow gp120 to bind the viral coreceptor, either CXCR4 or CCR5 [3?]. CD4 binding also induces the formation of a gp41 pre-hairpin intermediate, in which three hydrophobic grooves on the surface of a coiled coil formed by the heptad