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Ients with post-treatment symptoms often experience improvement of their symptoms within months158, although some patients can have severe joint and muscle pain, neurocognitive difficulties and/or incapacitating fatigue that persist for years178. The pathogenesis of these symptoms is unclear and might not be the same in all patients. These symptoms might be a part of a central sensitization syndro

Studies evaluatingOns to the statistical methods used in this study.Studies evaluating the efficacy of directly administered antiretroviral therapy (DAART) for the treatment of HIV-infected individuals have yielded mixed results. A systematic review and meta-analysis of randomized trials by Ford and colleagues found no evidence overall for DAART benefit [1]. However, both the Ford anal

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Ied [31,32]. These compounds, which include the prototypic compound NBD556 and its derivatives, mimic the effects of CD4 by inducing the exposure of the coreceptor-binding site on gp120 [31,33]. Although NBD-556 inhibits HIV-1 infection of CD4+CCR5+ cells, it can replace CD4 and thus enhance HIV-1 infection of CD42CCR5+ cells [31]. In view of their capacity to enhance infectivity, any potential ap

Ttle, 1962). Unlike classic KS, this endemic KS often can be rapidly fatal and is associated with significant morbidity and mortality, and is now recognized as one of the leading cancers in African children with HIV (Bayley, 1984; Downing et al., 1984). Importantly, KS is also known to develop after organ transplantation (posttransplant or iatrogenic KS; Penn, 1983). The fact that the immunosuppre

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