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T inducer of cytochrome P450 enzymes and is less likely to reduce concentrations of coadministered PIs, it is not yet widely available in developing countries, though access is rapidly expanding [22]. Further, RBT (and its main metabolite) are substrates of CYP3A, [23] leading to bidirectional drug interactions with PIs. For example, giving RTV, a potent inhibitor of CYP3A, together with RBT incre

S the same as sensitivity to dilution or drugs). The mistaken gestalt that sometimes comes to mind is that a stable microtubule is necessarily stiffer or less mobile than a labile microtubule. Some proteins that stabilize microtubules could also make them stiffer or less mobile, but this is not always true. For example, a microtubule could be stable but not as stiff as a microtubule that is labile

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