Xins in both forms of dementia include TNF-a, arachidonic acid, platelet activating factors (PAF), nitric oxide (NO), and quinolinic acid (QUIN) [17,53-59]. Nitric oxide is synthesized by endothelial cells, neurons, and macrophages and is thought to be associated with NMDA-type glutamate-initiated neurotoxicity [54]. TNF-a is released by HIV-1-infected microglia, and oligodendrocytes are particula

Es would most likely not have been affected. The measures of immune activation were not assessed at enrollment into the study cohort, and we therefore cannot make temporal inferences of a causal nature nor could we control for them in the multivariable Cox models. We used prevalence rate ratios (PRRs) to estimate the associations of interest as risk was our parameter of interest. We chose PRRs as

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Gel tryptic peptides of each spot ofinterest had been mixed with an acidic solid matrix for example cyano4hydroxy cinnamic acid CHCA, Bruker Daltonics matrix 10 mgml, which delivers high sensitivity and negligible matrix adduction throughout the laser absorption and subjected to laser radiation. The matrix was made in 70 acetonitrile and 0.03 TFA. 0.5 l on the peptide extracts mixed together w