Es would most likely not have been affected. The measures of immune activation were not assessed at enrollment into the study cohort, and we therefore cannot make temporal inferences of a causal nature nor could we control for them in the multivariable Cox models. We used prevalence rate ratios (PRRs) to estimate the associations of interest as risk was our parameter of interest. We chose PRRs as

Version; however, this finding was not confirmed by ulcers identified during STI examinations and may have included ulcers of nonherpetic etiologies. In contrast to the 51 reduction in HSV-2 incidence among women randomized to use a 1 tenofovir topical gel in CAPRISA 004, [9] our results suggest that tenofovir in daily oral FTC/TDF may reduce the occurrence of ulcers in individuals with HSV-2 in

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No differences by randomization group in the proportion of participants with 1 STI examination during which a perianal ulcer (FTC/TDF 3.5 vs. placebo 4.7 , P = 0.37) or groin ulcer (FTC/TDF 2.5 vs. placebo 1.9 , P = 0.51) was identified; results were similar after excluding participants with a positive syphilis rapid plasma reagin test at the same visit. However, symptoms that prompted STI exam

Was based on a evaluation on genetic as an alternative to epigenetic associationWas determined by a revi

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