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Al., 2001; Zozulya et al., 2001), are dedicated to olfaction. These receptors have typically been considered therapeutically unimportant, but this assessment may prove to be untenable. Along with taste receptors, volatile odorant receptors form an important sensory collective that modulates a host of deeply rooted animal behaviors such as feeding, mating, and memory formation. Unfortunately, these

D a randomized trial to evaluate the efficacy of DAART in OTPs.for this trial and supporting CONSORT checklist are available as supporting information; see Checklist S1 and Protocol S1.Methods Design and Follow-upWe conducted a randomized controlled trial comparing 12 months of DAART to self-administered therapy (SAT) in five Baltimore OTPs - 3 hospital associated (1 Veterans Administration) and 2

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