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Aseline by age group at enrollment, while Figure 1b shows HSV-2 incidence during follow-up by age group at enrollment. HSV-2, herpes simplex virus type 2. doi:10.1371/journal.pone.0091513.gDiscussionIn this analysis of participants in the iPrEx trial of daily oral FTC/TDF PrEP, we found no association between FTC/TDF and incidence of HSV-2 infection, even after accounting for actual use of FTC/TDF

Nopathy in the homosexual male. Am J Surg Pathol 9: 287?97. 36. Wood GS (1990) The immunohistology of lymph nodes in HIV infection: a review. Prog AIDS Pathol 2: 25?2. 37. Alter G, Teigen N, Ahern R, Streeck H, Meier A, et al. (2007) Evolution of innate and adaptive effector cell functions during acute HIV-1 infection. J Infect Dis 195: 1452?460. 38. Alter G, Teigen N, Davis BT, Addo MM, Suscovich

Vaccines. Recombinant poxvirus vaccines are worthy candidates given the wealth of experience using vaccinia for smallpox immunization programs in humans, and the development of recombinant techniques that enable insertion of substantial lengths of foreign DNA [1?]. More recently, attenuated strains of vaccinia have been developed (modified vaccinia Ankara; MVA) that are safer for use in young or i

Ignificantly longer lives. While HAART has been increasing the lifespan of those infected with HIV, it has also led to an increased prevalence of HAD [32-38]. As the pathology of HAD, like Alzheimer's Disease (AD), is commonly characterized by an increase in the amount of amyloid-beta (Ab) peptide in the brain [39], evidence suggesting microglia modulate the clearance of potentially neurotoxic Ab

R international relocation, using the intentions of typical employment and short-termR international rel

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En used to prevent disease24. Based on this idea, we explored the possibility that a single administration of a potent neutralizing anti-HIV MAb, in the setting of repeated low-dose (RLD) SHIV challenges, might protect for extended periods of time, thereby providing a proof of concept for periodic administration of MAb as an alternative to HIV-1 vaccination. We initially selected 3 MAbs for the RL